diff --git a/schemas/org.gnome.shell.extensions.dash-to-panel.gschema.xml b/schemas/org.gnome.shell.extensions.dash-to-panel.gschema.xml
index 81c51e1..2949347 100644
--- a/schemas/org.gnome.shell.extensions.dash-to-panel.gschema.xml
+++ b/schemas/org.gnome.shell.extensions.dash-to-panel.gschema.xml
@@ -695,6 +695,10 @@
       <summary>Provide monitor isolation</summary>
       <description>Dash shows only windows from the current monitor</description>
     </key>
+    <key type="b" name="isolate-monitors-with-single-panel">
+      <default>false</default>
+      <summary>Isolate monitors even with a single panel</summary>
+    </key>
     <key type="b" name="show-favorites-all-monitors">
       <default>true</default>
       <summary>Display the favorites on all monitors</summary>
diff --git a/src/appIcons.js b/src/appIcons.js
index da81d5c..f58fea5 100644
--- a/src/appIcons.js
+++ b/src/appIcons.js
@@ -1870,7 +1870,9 @@ export function getInterestingWindows(app, monitor, isolateMonitors) {
 
   if (
     monitor &&
-    (isolateMonitors || SETTINGS.get_boolean('isolate-monitors'))
+    (isolateMonitors || SETTINGS.get_boolean('isolate-monitors')) &&
+    (SETTINGS.get_boolean('multi-monitors') ||
+      SETTINGS.get_boolean('isolate-monitors-with-single-panel'))
   ) {
     windows = windows.filter(function (w) {
       return w.get_monitor() == monitor.index
diff --git a/src/panelManager.js b/src/panelManager.js
index 5fce29c..a9ea41f 100755
--- a/src/panelManager.js
+++ b/src/panelManager.js
@@ -495,7 +495,9 @@ export const PanelManager = class {
     }
 
     let isolateWorkspaces = SETTINGS.get_boolean('isolate-workspaces')
-    let isolateMonitors = SETTINGS.get_boolean('isolate-monitors')
+    let isolateMonitors =
+      !SETTINGS.get_boolean('multi-monitors') ||
+      SETTINGS.get_boolean('isolate-monitors')
 
     this.focusedApp = app
 
diff --git a/src/prefs.js b/src/prefs.js
index 27c86a1..cf70345 100644
--- a/src/prefs.js
+++ b/src/prefs.js
@@ -184,6 +184,7 @@ const Preferences = class {
     this._builder.add_from_file(
       this._path + '/ui/BoxIsolateWorkspacesOptions.ui',
     )
+    this._builder.add_from_file(this._path + '/ui/BoxIsolateMonitorsOptions.ui')
 
     // pages
     this._builder.add_from_file(this._path + '/ui/SettingsPosition.ui')
@@ -2608,6 +2609,37 @@ const Preferences = class {
       Gio.SettingsBindFlags.DEFAULT,
     )
 
+    this._settings.bind(
+      'isolate-monitors-with-single-panel',
+      this._builder.get_object('isolate_monitors_with_single_panel_switch'),
+      'active',
+      Gio.SettingsBindFlags.DEFAULT,
+    )
+
+    this._builder
+      .get_object('isolate_monitors_button')
+      .connect('clicked', () => {
+        let scrolledWindow = this._builder.get_object(
+          'box_isolate_monitors_options',
+        )
+
+        let dialog = this._createPreferencesDialog(
+          _('Isolate monitors options'),
+          scrolledWindow,
+          () => {
+            // restore default settings
+            this._settings.set_value(
+              'isolate-monitors-with-single-panel',
+              this._settings.get_default_value(
+                'isolate-monitors-with-single-panel',
+              ),
+            )
+          },
+        )
+
+        dialog.show()
+      })
+
     this._settings.bind(
       'overview-click-to-exit',
       this._builder.get_object('clicktoexit_switch'),
diff --git a/ui/BoxIsolateMonitorsOptions.ui b/ui/BoxIsolateMonitorsOptions.ui
new file mode 100644
index 0000000..8c37cc9
--- /dev/null
+++ b/ui/BoxIsolateMonitorsOptions.ui
@@ -0,0 +1,34 @@
+<?xml version='1.0' encoding='UTF-8'?>
+<interface>
+  <requires lib="gtk" version="4.18"/>
+  <requires lib="libadwaita" version="1.2"/>
+  <object class="GtkScrolledWindow" id="box_isolate_monitors_options">
+    <property name="height-request">300</property>
+    <property name="vexpand">True</property>
+    <property name="width-request">600</property>
+    <child>
+      <object class="GtkBox">
+        <property name="margin-bottom">32</property>
+        <property name="margin-end">32</property>
+        <property name="margin-start">32</property>
+        <property name="margin-top">32</property>
+        <property name="orientation">vertical</property>
+        <property name="spacing">24</property>
+        <child>
+          <object class="AdwPreferencesGroup">
+            <child>
+              <object class="AdwActionRow">
+                <property name="title" translatable="yes">Isolate monitors even when using a single panel</property>
+                <child>
+                  <object class="GtkSwitch" id="isolate_monitors_with_single_panel_switch">
+                    <property name="valign">center</property>
+                  </object>
+                </child>
+              </object>
+            </child>
+          </object>
+        </child>
+      </object>
+    </child>
+  </object>
+</interface>
diff --git a/ui/SettingsBehavior.ui b/ui/SettingsBehavior.ui
index bba198e..569da49 100644
--- a/ui/SettingsBehavior.ui
+++ b/ui/SettingsBehavior.ui
@@ -145,6 +145,20 @@
         <child>
           <object class="AdwActionRow">
             <property name="title" translatable="yes">Isolate monitors</property>
+            <child>
+              <object class="GtkButton" id="isolate_monitors_button">
+                <property name="receives-default">True</property>
+                <property name="valign">center</property>
+                <child>
+                  <object class="GtkImage" id="image_isolate_monitors_options">
+                    <property name="icon-name">emblem-system-symbolic</property>
+                  </object>
+                </child>
+                <style>
+                  <class name="circular"/>
+                </style>
+              </object>
+            </child>
             <child>
               <object class="GtkSwitch" id="multimon_multi_isolate_monitor_switch">
                 <property name="valign">center</property>