diff --git a/patches/series b/patches/series
index f1734883..64caf62a 100644
--- a/patches/series
+++ b/patches/series
@@ -1,5 +1,3 @@
-upstream-fixes/glue_core_pools.patch
-upstream-fixes/hardware_destructive_interference_size.patch
 upstream-fixes/missing-dependencies.patch
 upstream-fixes/fix-crash-without-enterprise-cloud-content-analysis.patch
 
diff --git a/patches/upstream-fixes/glue_core_pools.patch b/patches/upstream-fixes/glue_core_pools.patch
deleted file mode 100644
index 51ebd8c7..00000000
--- a/patches/upstream-fixes/glue_core_pools.patch
+++ /dev/null
@@ -1,27 +0,0 @@
-# glue_core_pools was partially removed in:
-# https://chromium-review.googlesource.com/c/chromium/src/+/5922801
-# This removes the remaining references needed to build
---- a/base/allocator/partition_allocator/partition_alloc.gni
-+++ b/base/allocator/partition_allocator/partition_alloc.gni
-@@ -239,9 +239,6 @@ declare_args() {
-   force_enable_raw_ptr_exclusion = false
- }
- 
--assert(!enable_pointer_compression_support || glue_core_pools,
--       "Pointer compression relies on core pools being contiguous.")
--
- declare_args() {
-   # We want to use RawPtrBackupRefImpl as the raw_ptr<> implementation
-   # iff BRP support is enabled. However, for purpose of performance
---- a/base/allocator/partition_allocator/src/partition_alloc/compressed_pointer.h
-+++ b/base/allocator/partition_allocator/src/partition_alloc/compressed_pointer.h
-@@ -21,9 +21,6 @@
- 
- #if PA_BUILDFLAG(ENABLE_POINTER_COMPRESSION)
- 
--#if !PA_BUILDFLAG(GLUE_CORE_POOLS)
--#error "Pointer compression only works with glued pools"
--#endif
- #if PA_CONFIG(DYNAMICALLY_SELECT_POOL_SIZE)
- #error "Pointer compression currently supports constant pool size"
- #endif
diff --git a/patches/upstream-fixes/hardware_destructive_interference_size.patch b/patches/upstream-fixes/hardware_destructive_interference_size.patch
deleted file mode 100644
index 4746a44f..00000000
--- a/patches/upstream-fixes/hardware_destructive_interference_size.patch
+++ /dev/null
@@ -1,25 +0,0 @@
-# hardware_destructive_interference_size was added in:
-# https://chromium-review.googlesource.com/c/chromium/src/+/5767325
-# then partially reverted in:
-# https://chromium-review.googlesource.com/c/chromium/src/+/5841144
-# This reverts the remaining change
---- a/components/media_router/common/providers/cast/channel/enum_table.h
-+++ b/components/media_router/common/providers/cast/channel/enum_table.h
-@@ -12,7 +12,6 @@
- 
- #include <cstdint>
- #include <cstring>
--#include <new>
- #include <optional>
- #include <ostream>
- #include <string_view>
-@@ -368,7 +367,8 @@ class EnumTable {
- 
-  private:
- #ifdef ARCH_CPU_64_BITS
--  alignas(std::hardware_destructive_interference_size)
-+  // Align the data on a cache line boundary.
-+  alignas(64)
- #endif
-       std::initializer_list<Entry> data_;
-   bool is_sorted_;